Endocrine Abstracts

QLS-H is a new, weighted QoL questionnaire developed for patients with hypopituitarism. We evaluated QLS-H data from UK patients in the HypoCCs International surveillance study, and compared results with a sample of the general UK population (n=1090).The QLS-H questionnaire was administered at baseline and at yearly intervals. Scores were corrected for age and gender differences, and expressed as Z-scores based on UK-specific reference ranges. Using this...

Hypothesis: High doses of vitamin D (VitD) improves dermal microcirculation (MC) in diabetic patients with type 2 diabetes mellitus (T2DM) and diabetic neuropathy (DN).Purpose: To study the effect of different VD doses on skin MC values in T2DM patients and DN.Materials and methods: Sixty-two non-smoking T2DM patients with DN were randomized into two groups: Group 1 received 5000 IU (G1) and Group 2 received 40000 IU (G2) of cholec...

Objectives: The objective of our – investigation is to find out the role of D3 vitamin deficiency – and calcium in patients with autoimmune thyroiditis and calcified nodules.Methods: The research has been carried out at “Muratsan” University Hospital and “Armenia” Medical Center, in 2013–2016.80 patients (ages ±4–0, of which 68 women and 12 men) with autoimmune thyroiditis and calcified ...

Background: Thyroid nodule is the most common endocrine disorder with the prevalence of more than 50% in adults. Majority of nodules are small in size and can be detected only by various imaging methods. Thyroid nodules are usually benign, asymptomatic, and do not need treatment. Growing and large symptomatic thyroid nodules are usually treated with thyroidectomy. Novel minimally invasive ablation techniques can be alternative to surgery. Percutaneous laser ablation is causing...

Aim: Diabetes is the most common metabolic disorder in the UK, affecting 20–30% of vascular inpatients. Diabetes is associated with increased mortality and adverse outcomes. Major vascular operations accompany an increased incidence of metabolic complications. There are trust guidelines outlining the optimal peri-operative management of diabetes. We audited compliance to this guideline in patients undergoing major vascular operations and measured patient outcomes.<p c...

Iain CAF Robinson, National Institute for Medical Research, Mill Hill, London, UK AbstractIain Robinson was born in 1949 and educated at the King Edward VII Grammar School in Sheffield before going to Worcester College, Oxford, to study physiology and medicine. Awarded first class honours in physiology and with medical studies deferred, Iain received an MRC studentship Award for studies on endocrine physiology in the D...

Introduction: Metabolic syndrome (MS) is a common disease with up to 25% of the total adult population and more than 45% of those over 60 years of age. When MS develops a complex of metabolic disorders that contribute to the development of vascular atherosclerotic diseases, such as abdominal obesity, hypertension, insulin resistance, dyslipidemia. Exchange disorders in MS are associated with the development of inflammation in organs and vessels, while the role of neutrophils i...

Aims: Presence of antinuclear antibodies (ANA) is correlated to tissue involutive lesions by microvascular alterations. The possible involvement of hypovitaminosis D as a negative immunomodulatory factor along with the presence of ANA and the incidence of chronic autoimmune thyroiditis (CAT) atrophic form is a complex mechanism with multiple pathological intercorrelations.Material and method: Inclusion criteria: patients - new cases diagnosed with CAT wi...

Objectives: Evaluation of functional thyroid alterations in correlation with hyperemesis gravidarum (HG).Material and method: Study performed on a group of 136 pregnant women with HG and a control group of 101 pregnant women. In both groups, cases with a known history of thyroid disease, molar pregnancy, multiple pregnancies or other systemic chronic diseases were excluded. Patients were clinically and serologically examined (TSH, FT4, ATPO, TRAb), the r...

Introduction: Metabolic syndrome (MS) is a disease that develops in obesity in adult patients with the development of numerous metabolic and vascular disorders. In patients with MS, the risk of developing cardiovascular diseases is increased compared to the general population by 1.78 times as a whole and 2.25 times in women. Currently, the number of overweight children and the development of metabolic complications such as fatty liver, hypertension, and type 2 diabetes are inc...